Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | NOS2 | P35228 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19690771 | 0.80 | — | — | |
| SCHEMBL19354579 | 0.79 | — | — | |
| SCHEMBL1522730 | 0.79 | — | — | |
| SCHEMBL497608 | 0.75 | — | — | |
| SCHEMBL9475223 | 0.75 | KDM4E (0.38) | KDM4ETSHRHTTMAPTSMN1; SMN2 | |
| SCHEMBL2044222 | 0.75 | SMN1; SMN2 (0.43) | KDM4ETSHRHTTMAPTSMN1; SMN2 | |
| SCHEMBL28181487 | 0.74 | SMN1; SMN2 (0.42) | KDM4ETSHRHTTMAPTSMN1; SMN2 | |
| SCHEMBL9396417 | 0.74 | HSD17B10 (0.39) | KDM4ETSHRHTTMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11286601 | 0.73 | — | — | |
| SCHEMBL12096487 | 0.72 | SMN1; SMN2 (0.36) | KDM4ETSHRHTTMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0867437-B1 | \"Method of preparing a thiophene-containing or furan -containing conjugated compound and precursor compound used therein\". | KONINKL PHILIPS ELECTRONICS NV (NL) | 2002-11-13 | — | — | EP | claimed |
| US-6184540-B1 | SEMICONDUCTOR HAVING A LAYER OF A POLYTHIOPHENE DERIVED FROM A SOLUBLE PRECURSOR COMPOUND OF TETRAHYDROTHIOPHENE OR TETRAHYDROFURAN UNITS HAVING THERMALLY SEPARABLE ARYL- OR ALKYL-THIO SUBSTITUENTS, WHICH CAN BE PROCESSED FROM SOLUTION | U.S. PHILIPS CORPORATION | 2001-02-06 | — | — | US | claimed |
| US-6124475-A | Method of preparing a thiophene-containing or furan-containing conjugated compound and precursor compound used therein | U.S. PHILIPS CORPORATION (US) | 2000-09-26 | — | — | US | claimed |
| US-5919951-A | Method of preparing a thiophene-containing or furan-containing conjugated compound and precursor compound used therein | U.S. PHILIPS CORPORATION (US) | 1999-07-06 | — | — | US | claimed |
| EP-0867437-A1 | \"Method of preparing a thiophene-containing or furan -containing conjugated compound and precursor compound used therein\". | Koninklijke Philips Electronics N.V. (NL) | 1998-09-30 | — | — | EP | claimed |
| EP-0867437-B1 | \"Method of preparing a thiophene-containing or furan -containing conjugated compound and precursor compound used therein\". | KONINKL PHILIPS ELECTRONICS NV (NL) | 2002-11-13 | — | — | EP | disclosed |
| US-6184540-B1 | SEMICONDUCTOR HAVING A LAYER OF A POLYTHIOPHENE DERIVED FROM A SOLUBLE PRECURSOR COMPOUND OF TETRAHYDROTHIOPHENE OR TETRAHYDROFURAN UNITS HAVING THERMALLY SEPARABLE ARYL- OR ALKYL-THIO SUBSTITUENTS, WHICH CAN BE PROCESSED FROM SOLUTION | U.S. PHILIPS CORPORATION | 2001-02-06 | — | — | US | disclosed |
| US-6124475-A | Method of preparing a thiophene-containing or furan-containing conjugated compound and precursor compound used therein | U.S. PHILIPS CORPORATION (US) | 2000-09-26 | — | — | US | disclosed |
| US-5919951-A | Method of preparing a thiophene-containing or furan-containing conjugated compound and precursor compound used therein | U.S. PHILIPS CORPORATION (US) | 1999-07-06 | — | — | US | disclosed |
| EP-0867437-A1 | \"Method of preparing a thiophene-containing or furan -containing conjugated compound and precursor compound used therein\". | Koninklijke Philips Electronics N.V. (NL) | 1998-09-30 | — | — | EP | disclosed |
| EP-0322033-A2 | New 2,5-diaryl tetrahydrofurans and analogs thereof as paf antagonists | MERCK & CO. INC. (US) | 1989-06-28 | — | — | EP | disclosed |
| EP-0199324-A2 | New 2,5-diaryl tetryhydrofurans and analogs thereof as paf antagonists | MERCK & CO. INC. (US) | 1986-10-29 | — | — | EP | disclosed |