Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12096487 | 0.89 | SMN1; SMN2 (0.36) | KDM4ETSHRHTTMAPTSMN1; SMN2 | |
| SCHEMBL19690771 | 0.78 | — | — | |
| SCHEMBL7475896 | 0.75 | KDM4E (0.42) | KDM4ETSHRHTTMAPTSMN1; SMN2 | |
| SCHEMBL2044222 | 0.73 | SMN1; SMN2 (0.43) | KDM4ETSHRHTTMAPTSMN1; SMN2 | |
| SCHEMBL19354579 | 0.73 | — | — | |
| SCHEMBL1522730 | 0.73 | — | — | |
| SCHEMBL9396417 | 0.72 | HSD17B10 (0.39) | KDM4ETSHRHTTMAPTSMN1; SMN2 | |
| SCHEMBL28181487 | 0.72 | SMN1; SMN2 (0.42) | KDM4ETSHRHTTMAPTSMN1; SMN2 | |
| SCHEMBL454997 | 0.69 | MAPT (0.43) | KDM4ETSHRHTTMAPTSMN1; SMN2 | |
| SCHEMBL497608 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185363-A | Administering for treatment of inflammatory diseases | ABBOTT LABORATORIES (US) | 1993-02-09 | — | — | US | disclosed |