Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470473 | 0.87 | HPGD (0.30) | — | |
| SCHEMBL7470660 | 0.80 | ELANE (0.35) | — | |
| SCHEMBL6182747 | 0.78 | RARA (0.36) | — | |
| SCHEMBL6185269 | 0.77 | KDM4E (0.38) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7470667 | 0.76 | RARA (0.35) | — | |
| SCHEMBL6185465 | 0.75 | — | — | |
| SCHEMBL6200595 | 0.74 | DHODH (0.34) | MEN1KMT2A | |
| SCHEMBL7468773 | 0.74 | LMNA (0.30) | KMT2A | |
| SCHEMBL9118907 | 0.71 | NPC1 (0.30) | MEN1KMT2A | |
| SCHEMBL8491762 | 0.69 | ERCC5 (0.45) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636622-B1 | Isoxazole derivatives and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-10-23 | — | — | EP | disclosed |
| EP-1160244-A1 | Isoxazole derivatives and their use as herbicides | RHONE-POULENC AGRICULTURE LIMITED (GB) | 2001-12-05 | — | — | EP | disclosed |
| US-5489570-A | PRE- OR POST-EMERGENCE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1996-02-06 | — | — | US | disclosed |
| WO-1995025099-A1 | 2-CYANO-1,3-DIONE DERIVATIVES USEFUL AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1995-09-21 | — | — | WO | disclosed |
| EP-0636622-A1 | Isoxazole derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-02-01 | — | — | EP | disclosed |