Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.37 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27786419 | 0.84 | CSNK2A1 (0.41) | TP53HTTCSNK2A1MEN1KMT2A | |
| SCHEMBL11528407 | 0.77 | TP53 (0.48) | TP53HTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8378141 | 0.77 | ALDH1A1 (0.53) | TP53HTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7352290 | 0.76 | KDM4E (0.43) | TP53HTTCSNK2A1MEN1KMT2A | |
| SCHEMBL2420457 | 0.75 | CSNK2A1 (0.52) | TP53HTTCSNK2A1MEN1KMT2A | |
| SCHEMBL27880271 | 0.73 | TP53 (0.50) | TP53HTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1668024 | 0.72 | TP53 (0.53) | TP53HTTMEN1KMT2ASMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL27451904 | 0.70 | TP53 (0.51) | TP53HTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL472304 | 0.70 | ABCC1 (0.54) | TP53HTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27876488 | 0.70 | HTT (0.48) | TP53HTTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001009117-A1 | TRICYCLIC COMPOUNDS AS GLYCINE TRANSPORT INHIBITORS | ALLELLIX NEUROSCIENCE INC. (US) | 2001-02-08 | — | — | WO | disclosed |
| US-6162824-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | ALLELIX NEUROSCIENCE INC. | 2000-12-19 | — | — | US | disclosed |