Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9221117 | 0.86 | TP53 (0.59) | ALDH1A1MAPTKDM4EGAACYP3A4 | |
| SCHEMBL28174299 | 0.86 | MAPT (0.41) | ALDH1A1MAPTKDM4EGAACYP3A4 | |
| SCHEMBL3418853 | 0.81 | MAOA (0.50) | ALDH1A1MAPTKDM4EGAACYP3A4 | |
| SCHEMBL11235298 | 0.80 | ALDH1A1 (0.58) | ALDH1A1MAPTKDM4EGAACYP3A4 | |
| Hydrochloric Acid SCHEMBL2876219 | 0.80 | MAOA (0.49) | ALDH1A1MAPTGAACYP3A4MEN1 | |
| SCHEMBL11528407 | 0.79 | TP53 (0.48) | ALDH1A1MAPTKDM4ETP53HTT | |
| SCHEMBL2810702 | 0.77 | ALDH1A1 (0.52) | ALDH1A1MAPTKDM4EGAACYP3A4 | |
| SCHEMBL2810699 | 0.77 | ALDH1A1 (0.52) | ALDH1A1MAPTKDM4EGAACYP3A4 | |
| SCHEMBL7476029 | 0.77 | TP53 (0.46) | ALDH1A1KDM4ETP53HTTMEN1 | |
| SCHEMBL27930270 | 0.76 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4EGAACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874608-A | Process for the preparation of esters of aromatic carboxylic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-02-23 | — | — | US | disclosed |
| EP-0431387-B1 | Basic polysaccharides | WOLFF WALSRODE AG (DE) | 1995-09-06 | — | — | EP | disclosed |
| EP-0431387-A1 | Basic polysaccharides | Wolff Walsrode Aktiengesellschaft (DE) | 1991-06-12 | — | — | EP | disclosed |