Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 20/20 | 0.52 |
| ▸ | HTR1B | P28222 | 18/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8185801 | 0.84 | HTR1D (0.68) | HTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL7479279 | 0.76 | HTR1D (0.79) | HTR1DHTR1B | |
| SCHEMBL8699524 | 0.74 | HTR1D (0.51) | HTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL7483896 | 0.72 | HTR1D (0.62) | HTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL8427579 | 0.70 | HTR1D (0.69) | HTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL8427576 | 0.70 | HTR1D (0.69) | HTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL8699528 | 0.70 | HTR1D (0.42) | HTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL8697124 | 0.69 | HTR1D (0.42) | HTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL8474241 | 0.69 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL8471754 | 0.69 | HTR1D (1.00) | HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925302-B1 | PALLADIUM CATALYZED INDOLIZATION | MERCK & CO INC (US) | 2002-11-20 | — | — | EP | claimed |
| EP-0925302-B1 | PALLADIUM CATALYZED INDOLIZATION | MERCK & CO INC (US) | 2002-11-20 | — | — | EP | disclosed |
| US-5808064-A | HYDROSILATION OF AN INDOLE AS CHEMICAL INTERMEDIATE | MERCK & CO., INC. (US) | 1998-09-15 | — | — | US | disclosed |