Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 20/20 | 0.42 |
| ▸ | HTR1B | P28222 | 18/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8694459 | 0.89 | HTR1D (0.33) | HTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL7476071 | 0.70 | HTR1D (0.52) | HTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL8662190 | 0.65 | HTR1D (0.48) | HTR1DHTR1B | |
| SCHEMBL8693793 | 0.65 | HTR1D (0.53) | HTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL8459340 | 0.63 | HTR1D (0.46) | HTR1DHTR1B | |
| SCHEMBL8649047 | 0.62 | HTR1D (0.52) | HTR1DHTR1B | |
| SCHEMBL8693142 | 0.61 | HTR1D (0.50) | HTR1DHTR1B | |
| SCHEMBL8695460 | 0.60 | HTR1D (0.58) | HTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL8693154 | 0.60 | HTR1D (0.58) | HTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL7477312 | 0.60 | HTR1D (0.83) | HTR1DHTR1BHTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808064-A | HYDROSILATION OF AN INDOLE AS CHEMICAL INTERMEDIATE | MERCK & CO., INC. (US) | 1998-09-15 | — | — | US | disclosed |