Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 3/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.65 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.65 |
| ▸ | HTR1A | P08908 | 2/20 | 0.65 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.65 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.65 |
| ▸ | DRD1 | P21728 | 2/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.65 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.65 |
| ▸ | DRD3 | P35462 | 2/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.65 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.65 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.65 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.65 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.65 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.65 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.65 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7476461 | 0.99 | TBXA2R (0.64) | TBXA2RADRA1ASLC6A3ABCB11HTR1A | |
| SCHEMBL9485304 | 0.95 | ABCB11 (0.72) | TBXA2RADRA1ASLC6A3ABCB11HTR1A | |
| SCHEMBL7479783 | 0.90 | CYP2C9 (0.72) | TBXA2RADRA1ASLC6A3ABCB11HTR1A | |
| SCHEMBL3032376 | 0.90 | CYP2C9 (0.61) | TBXA2RADRA1ASLC6A3ABCB11HTR1A | |
| Hydrochloric Acid SCHEMBL7479775 | 0.89 | CYP2C9 (0.71) | TBXA2RADRA1ASLC6A3ABCB11HTR1A | |
| SCHEMBL3017208 | 0.88 | CYP2C9 (0.73) | TBXA2RADRA1ASLC6A3ABCB11HTR1A | |
| SCHEMBL10894427 | 0.87 | ALDH1A1 (0.62) | TBXA2RADRA1ASLC6A3ABCB11HTR1A | |
| SCHEMBL11777899 | 0.86 | CYP2C9 (0.67) | TBXA2RADRA1ASLC6A3ABCB11HTR1A | |
| SCHEMBL9485314 | 0.86 | CYP2C9 (0.81) | TBXA2RADRA1ASLC6A3ABCB11HTR1A | |
| SCHEMBL8790137 | 0.85 | TBXA2R (0.49) | TBXA2RADRA1ASLC6A3ABCB11HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0779277-B1 | 1,4-DIHYDROPYRIDINE DERIVATIVE | MERCIAN CORP (JP) | 2002-07-10 | — | — | EP | disclosed |
| US-5760238-A | ANTIISCHEMIC AGENTS | MERCIAN CORPORATION (JP) | 1998-06-02 | — | — | US | disclosed |
| EP-0779277-A1 | 1,4-DIHYDROPYRIDINE DERIVATIVE | MERCIAN CORPORATION (JP) | 1997-06-18 | — | — | EP | disclosed |