Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 7/20 | 0.65 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.65 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | RGS12 | O14924 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 3/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9395829 | 0.84 | OPRM1 (0.64) | OPRL1OPRM1OPRD1OPRK1PGR | |
| SCHEMBL30910142 | 0.81 | OPRL1 (0.86) | OPRL1OPRM1OPRD1OPRK1CHRM2 | |
| SCHEMBL26092381 | 0.81 | OPRL1 (0.86) | OPRL1OPRM1OPRD1OPRK1CHRM2 | |
| SCHEMBL7481411 | 0.80 | OPRL1 (0.52) | OPRL1OPRM1OPRD1OPRK1PGR | |
| SCHEMBL1270635 | 0.79 | OPRM1 (0.74) | OPRL1OPRM1OPRD1OPRK1CHRM2 | |
| SCHEMBL1272232 | 0.79 | OPRL1 (1.00) | OPRL1OPRM1OPRD1OPRK1PGR | |
| SCHEMBL1271664 | 0.79 | OPRM1 (0.74) | OPRL1OPRM1OPRD1OPRK1PGR | |
| SCHEMBL1271637 | 0.79 | OPRM1 (0.74) | OPRL1OPRM1OPRD1OPRK1CHRM2 | |
| SCHEMBL7488793 | 0.77 | OPRM1 (0.56) | OPRL1OPRM1OPRD1OPRK1KDM4E | |
| SCHEMBL12029042 | 0.77 | OPRM1 (0.84) | OPRL1OPRM1OPRD1OPRK1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799224-B1 | QUINOXALINES AND DRUGS PREPARED THEREFROM | BASF AG (DE) | 2002-04-17 | — | — | EP | disclosed |
| US-5852017-A | 2,3(1H,4H)-quinoxalinediones | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-22 | — | — | US | disclosed |
| US-5849743-A | Quinoxalines and drugs prepared therefrom | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-15 | — | — | US | disclosed |
| EP-0572852-B1 | Quinoxalin-2,3(1H,4H)-diones used as medicine | BASF AG (DE) | 1998-10-21 | — | — | EP | disclosed |
| US-5714489-A | 2,3(1H,4H)quinoxalinedione | BASF AKTIENGESELLSCHAFT (DE) | 1998-02-03 | — | — | US | disclosed |
| WO-1996019476-A1 | NOVEL QUINOXALINES AND DRUGS PREPARED THEREFROM | BASF AKTIENGESELLSCHAFT (DE) | 1996-06-27 | — | — | WO | disclosed |
| EP-0572852-A1 | Quinoxalin-2,3(1H,4H)-diones used as medicine | BASF Aktiengesellschaft (DE) | 1993-12-08 | — | — | EP | disclosed |