Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 7/20 | 0.56 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | PRKDC | P78527 | 1/20 | 0.44 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17335974 | 0.79 | ERCC1 (0.62) | OPRM1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7476479 | 0.77 | OPRL1 (0.65) | OPRM1OPRL1OPRD1OPRK1KDM4E | |
| SCHEMBL9395829 | 0.76 | OPRM1 (0.64) | OPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL8607620 | 0.75 | ALDH1A1 (0.46) | OPRM1OPRL1OPRD1OPRK1KDM4E | |
| SCHEMBL8609111 | 0.74 | PSMB8 (0.53) | KDM4EALDH1A1HPGDHSD17B10PSMB8 | |
| SCHEMBL1270635 | 0.74 | OPRM1 (0.74) | OPRM1OPRL1OPRD1OPRK1OGFRL1 | |
| SCHEMBL30910142 | 0.73 | OPRL1 (0.86) | OPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL26092381 | 0.73 | OPRL1 (0.86) | OPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL1271514 | 0.73 | OPRL1 (0.64) | OPRM1OPRL1OPRD1OPRK1KDM4E | |
| SCHEMBL1271664 | 0.71 | OPRM1 (0.74) | OPRM1OPRL1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799224-B1 | QUINOXALINES AND DRUGS PREPARED THEREFROM | BASF AG (DE) | 2002-04-17 | — | — | EP | disclosed |
| US-5852017-A | 2,3(1H,4H)-quinoxalinediones | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-22 | — | — | US | disclosed |
| US-5849743-A | Quinoxalines and drugs prepared therefrom | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-15 | — | — | US | disclosed |
| EP-0572852-B1 | Quinoxalin-2,3(1H,4H)-diones used as medicine | BASF AG (DE) | 1998-10-21 | — | — | EP | disclosed |
| US-5714489-A | 2,3(1H,4H)quinoxalinedione | BASF AKTIENGESELLSCHAFT (DE) | 1998-02-03 | — | — | US | disclosed |
| EP-0799224-A1 | NOVEL QUINOXALINES AND DRUGS PREPARED THEREFROM | BASF AKTIENGESELLSCHAFT (DE) | 1997-10-08 | — | — | EP | disclosed |
| WO-1996019476-A1 | NOVEL QUINOXALINES AND DRUGS PREPARED THEREFROM | BASF AKTIENGESELLSCHAFT (DE) | 1996-06-27 | — | — | WO | disclosed |
| EP-0572852-A1 | Quinoxalin-2,3(1H,4H)-diones used as medicine | BASF Aktiengesellschaft (DE) | 1993-12-08 | — | — | EP | disclosed |