Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SNCA | P37840 | 4/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7476502 | 1.00 | JUN (0.48) | JUNNFKB1ALDH1A1ALOX5TRPA1 | |
| SCHEMBL1308464 | 0.91 | ALDH1A1 (0.58) | JUNNFKB1ALDH1A1ALOX5TRPA1 | |
| SCHEMBL1308466 | 0.91 | ALDH1A1 (0.58) | JUNNFKB1ALDH1A1ALOX5TRPA1 | |
| SCHEMBL15401259 | 0.88 | JUN (0.52) | JUNNFKB1ALDH1A1ALOX5MAPT | |
| SCHEMBL4010937 | 0.88 | JUN (0.52) | JUNNFKB1ALDH1A1ALOX5MAPT | |
| SCHEMBL4010936 | 0.88 | JUN (0.52) | JUNNFKB1ALDH1A1ALOX5MAPT | |
| SCHEMBL4004419 | 0.85 | JUN (0.54) | JUNNFKB1ALDH1A1ALOX5LMNA | |
| SCHEMBL4004416 | 0.85 | JUN (0.54) | JUNNFKB1ALDH1A1ALOX5LMNA | |
| Oxalic Acid SCHEMBL1678014 | 0.81 | ALDH1A1 (0.54) | JUNNFKB1ALDH1A1ALOX5TRPA1 | |
| Oxalic Acid SCHEMBL1678015 | 0.81 | ALDH1A1 (0.54) | JUNNFKB1ALDH1A1ALOX5TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0771796-B1 | Substituted S-triazines and process for their preparation | AGFA GEVAERT (BE) | 2002-06-19 | — | — | EP | disclosed |
| EP-0771796-A1 | Substituted S-triazines and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-07 | — | — | EP | disclosed |