Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7582716 | 0.83 | CNR2 (0.46) | CNR2ALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL4403632 | 0.79 | CNR2 (0.60) | CNR2ALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL7426856 | 0.77 | MEN1 (0.47) | CNR2ALDH1A1MAPTHPGDHTT | |
| SCHEMBL1502220 | 0.73 | CYP11B1 (0.47) | HRH3MAOBMAPK1PDE4BBCHE | |
| SCHEMBL12635690 | 0.72 | MAOB (0.60) | MAOBPOLBBCHE | |
| SCHEMBL379281 | 0.72 | MAOB (0.67) | MAOBBCHE | |
| SCHEMBL22096045 | 0.71 | STAT5B (0.61) | ALDH1A1LMNASMN1; SMN2MAOBTSHR | |
| SCHEMBL2137838 | 0.70 | MRGPRX4 (0.69) | MAOBBCHE | |
| SCHEMBL9016444 | 0.70 | ALOX5 (0.52) | ALDH1A1HRH3MAOBMAPTKMT2A | |
| SCHEMBL6362679 | 0.69 | NR1H2 (0.57) | ALDH1A1LMNAMAPTHTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002022584-A1 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2002-03-21 | — | — | WO | disclosed |