Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | KHK | P50053 | 3/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7467625 | 0.88 | F10 (0.37) | F10F2KHKDRD2HRH3 | |
| SCHEMBL7479561 | 0.86 | RORC (0.39) | F10F2KHKHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL7559934 | 0.84 | F2 (0.34) | F10F2KHKS1PR1CYP1A2 | |
| Hydrochloric Acid SCHEMBL7480546 | 0.82 | F10 (0.38) | F10F2KHKHRH3 | |
| Hydrochloric Acid SCHEMBL7475209 | 0.80 | KDM4E (0.38) | F10F2KHKDRD2DRD3 | |
| SCHEMBL7478455 | 0.79 | F10 (0.37) | F10F2KHKHRH3 | |
| SCHEMBL7478466 | 0.79 | F10 (0.37) | F10F2KHKHRH3 | |
| SCHEMBL7476632 | 0.78 | F10 (0.36) | F10F2KHKHRH3 | |
| SCHEMBL7476624 | 0.78 | F10 (0.36) | F10F2KHKHRH3 | |
| SCHEMBL7465362 | 0.78 | F10 (0.37) | F10F2KHKHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777667-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | Dr. Karl Thomae GmbH (DE) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996005194-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | DR. KARL THOMAE GMBH (DE) | 1996-02-22 | — | — | WO | disclosed |