Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.36 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7460922 | 1.00 | BCAT2 (0.47) | BCAT2NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL5248171 | 0.84 | BCAT2 (0.68) | BCAT2NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL7466075 | 0.83 | ADRB3 (0.48) | BCAT2CYP1A2CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL7466916 | 0.83 | ADRB3 (0.48) | BCAT2CYP1A2CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL7474893 | 0.83 | ADRB3 (0.48) | BCAT2CYP1A2CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL7459877 | 0.82 | MAPT (0.40) | LMNACYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL7464034 | 0.82 | MAPT (0.40) | LMNACYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL7470481 | 0.82 | MAPT (0.40) | LMNACYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL3657534 | 0.78 | GAA (0.48) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL7460467 | 0.78 | BCAT2 (0.40) | BCAT2NPC1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0907635-B1 | HALOGEN SUBSTITUTED CARBAMATE COMPOUNDS FROM 2-PHENYL-1,2-ETHANEDIOL | SK CORP (KR) | 2002-09-25 | — | — | EP | disclosed |
| US-20010034365-A1 | Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol | CHOI YONG MOON (US) | 2001-10-25 | — | — | US | disclosed |
| US-6127412-A | TREATMENT OF DISORDERS OF THE CENTRAL NERVOUS SYSTEM, ESPECIALLY AS ANTICONVULSANTS, ANTIEPILEPTIC AND NEUROPROTECTIVE AGENTS AND CENTRALLY ACTING MUSCLE RELAXANTS | SK CORPORATION (US) | 2000-10-03 | — | — | US | disclosed |
| US-6103759-A | COMPRISING PURE ENANTIOMERIC FORMS, AS WELL AS ENANTIOMERIC MIXTURES, OF (2-(2-CHLOROPHENYL)-2-HYDROXYETHYL)OXYCARBOXAMIDE; USEFUL FOR TRATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | SK CORPORATION (US) | 2000-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010034365-A1 | Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol | DDT, GRIK2, GABRD | BCAT2 603/4885NPC1 1768/4885RAB9A 3412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.