Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | NOS3 | P29474 | 2/20 | 0.43 |
| ▸ | NOS1 | P29475 | 2/20 | 0.43 |
| ▸ | NOS2 | P35228 | 2/20 | 0.43 |
| ▸ | F11 | P03951 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42406 | 0.80 | — | — | |
| Charcoal, Activated SCHEMBL30894562 | 0.78 | — | — | |
| Benzylamine SCHEMBL27497416 | 0.76 | LOXL2 (0.78) | LOXL2TAAR1F11CYP1A2CYP2D6 | |
| Chlorobenzene SCHEMBL28806863 | 0.76 | TSHR (0.44) | CYP1A2TSHRCYP2C19ENPP2PTPN1 | |
| Benzylamine SCHEMBL27781209 | 0.73 | LOXL2 (0.93) | LOXL2TAAR1CYP1A2CYP2D6CYP2C9 | |
| Phenylboronic Acid SCHEMBL28488393 | 0.72 | F11 (0.68) | LOXL2TAAR1F11CYP1A2CYP2D6 | |
| Benzylamine SCHEMBL11703154 | 0.72 | LOXL2 (0.70) | LOXL2TAAR1NOS3NOS1NOS2 | |
| Benzylamine SCHEMBL373 | 0.71 | — | — | |
| Benzylamine SCHEMBL10707644 | 0.71 | LOXL2 (1.00) | LOXL2TAAR1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL19242392 | 0.71 | LOXL2 (1.00) | LOXL2TAAR1CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240169-A1 | PEPTIDE BETA-TURN MIMETIC COMPOUNDS AND PROCESSES FOR MAKING THEM | THE PROCTER & GAMBLE COMPANY (US) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001046197-A1 | PEPTIDE β-TURN MIMETIC COMPOUNDS AND PROCESSES FOR MAKING THEM | THE PROCTER & GAMBLE COMPANY (US) | 2001-06-28 | — | — | WO | disclosed |