Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 16/20 | 0.32 |
| ▸ | DRD3 | P35462 | 14/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7476926 | 1.00 | DRD2 (0.32) | DRD2DRD3SMYD3HTR1AACHE | |
| SCHEMBL8562566 | 0.91 | DRD2 (0.35) | DRD2DRD3HTR1AACHE | |
| SCHEMBL8562570 | 0.91 | DRD2 (0.35) | DRD2DRD3HTR1AACHE | |
| SCHEMBL8562233 | 0.88 | ESR1 (0.39) | — | |
| SCHEMBL8562237 | 0.88 | ESR1 (0.39) | — | |
| SCHEMBL7472292 | 0.82 | F2 (0.34) | DRD2DRD3 | |
| SCHEMBL7472286 | 0.82 | F2 (0.34) | DRD2DRD3 | |
| SCHEMBL7472786 | 0.80 | MGAT2 (0.31) | — | |
| SCHEMBL7472793 | 0.80 | MGAT2 (0.31) | — | |
| Hydrochloric Acid SCHEMBL8560128 | 0.80 | DRD2 (0.36) | DRD2DRD3HTR1AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777667-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | Dr. Karl Thomae GmbH (DE) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996005194-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | DR. KARL THOMAE GMBH (DE) | 1996-02-22 | — | — | WO | disclosed |