Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 9/20 | 0.80 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3304163 | 0.90 | ABCC9 (0.88) | ABCC9ABCB1KDM4E | |
| SCHEMBL7481849 | 0.90 | ABCC9 (0.88) | ABCC9ABCB1KDM4E | |
| SCHEMBL3305829 | 0.90 | ABCC9 (0.88) | ABCC9ABCB1KDM4E | |
| SCHEMBL7479202 | 0.90 | ABCC9 (0.88) | ABCC9ABCB1KDM4E | |
| SCHEMBL7479207 | 0.90 | ABCC9 (0.88) | ABCC9ABCB1KDM4E | |
| SCHEMBL8341346 | 0.89 | ABCC9 (1.00) | ABCC9ABCB1KDM4E | |
| SCHEMBL8341353 | 0.89 | ABCC9 (1.00) | ABCC9ABCB1KDM4E | |
| SCHEMBL8341342 | 0.89 | ABCC9 (1.00) | ABCC9ABCB1KDM4E | |
| SCHEMBL8341798 | 0.88 | ABCC9 (1.00) | ABCC9ABCB1 | |
| SCHEMBL8341802 | 0.88 | ABCC9 (1.00) | ABCC9ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587645-B1 | BENZO- AND PYRIDOPYRAN DERIVATIVES HAVING ANXIOLYTIC AND ANTI-CONVULSANT ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 2002-02-27 | — | — | EP | claimed |
| WO-1994012173-A1 | BENZOPYRON ANALOGUES FOR THE TREATMENT OF ANXIETY, MANIA, DEPRESSION OR WITHDRAWAL SYMPTOMS | SMITHKLINE BEECHAM PLC (GB) | 1994-06-09 | — | — | WO | claimed |
| EP-0587645-B1 | BENZO- AND PYRIDOPYRAN DERIVATIVES HAVING ANXIOLYTIC AND ANTI-CONVULSANT ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 2002-02-27 | — | — | EP | disclosed |
| EP-1108718-A2 | Trans-6-Acetyl-4S-(4-fluorobenzoylamino)-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-3R-ol | SMITHKLINE BEECHAM PLC (GB) | 2001-06-20 | — | — | EP | disclosed |
| US-5889044-A | Benzo- and pyridopyran derivatives having anxiolytic and anti-convulsant activity | SMITHKLINE BEECHAM P.L.C. (GB) | 1999-03-30 | — | — | US | disclosed |
| US-5624954-A | Benzo- and pyridopyran derivatives having anxiolytic and anti-convulsant activity | SMITHKLINE BEECHAM P.L.C. (GB) | 1997-04-29 | — | — | US | disclosed |
| WO-1994012173-A1 | BENZOPYRON ANALOGUES FOR THE TREATMENT OF ANXIETY, MANIA, DEPRESSION OR WITHDRAWAL SYMPTOMS | SMITHKLINE BEECHAM PLC (GB) | 1994-06-09 | — | — | WO | disclosed |