Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 9/20 | 0.88 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7479202 | 1.00 | ABCC9 (0.88) | ABCC9ABCB1KDM4E | |
| SCHEMBL7479207 | 1.00 | ABCC9 (0.88) | ABCC9ABCB1KDM4E | |
| SCHEMBL3304163 | 1.00 | ABCC9 (0.88) | ABCC9ABCB1KDM4E | |
| SCHEMBL7481849 | 1.00 | ABCC9 (0.88) | ABCC9ABCB1KDM4E | |
| SCHEMBL8341342 | 0.93 | ABCC9 (1.00) | ABCC9ABCB1KDM4E | |
| SCHEMBL8341353 | 0.93 | ABCC9 (1.00) | ABCC9ABCB1KDM4E | |
| SCHEMBL8341346 | 0.93 | ABCC9 (1.00) | ABCC9ABCB1KDM4E | |
| SCHEMBL10504985 | 0.90 | ABCC9 (0.89) | ABCC9ABCB1KDM4E | |
| SCHEMBL10504977 | 0.90 | ABCC9 (0.89) | ABCC9ABCB1KDM4E | |
| SCHEMBL10504992 | 0.90 | ABCC9 (0.89) | ABCC9ABCB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099752-A1 | PHARMACEUTICAL COMPOSITION CONTAINING BICYCLIC TYPE COMPOUNDS | SMITHKLINE BEECHAM PLC. (GB) | 2010-04-22 | — | — | US | claimed |
| US-20070088064-A1 | PHARMACEUTICAL COMPOSITION CONTAINING BICYCLIC TYPE COMPOUNDS | SMITHKLINE BEECHAM PLC | 2007-04-19 | — | — | US | claimed |
| US-20030236410-A1 | Pharmaceutical composition containing bicyclic type compounds | SMITHKLINE BEECHAM P.L.C. | 2003-12-25 | — | — | US | claimed |
| US-20020123630-A1 | Pharmaceutical composition containing bicyclic type compounds | SMITHKLINE BEECHAM P.L.C. | 2002-09-05 | — | — | US | claimed |
| US-20010021780-A1 | Pharmaceutical composition containing bicyclic type compounds | SMITHKLINE BEECHAM P.L.C. | 2001-09-13 | — | — | US | claimed |
| EP-0673374-B1 | PHARMACEUTICAL COMPOSITION CONTAINING BICYCLIC TYPE COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 2000-03-01 | — | — | EP | claimed |
| WO-1994013657-A1 | PHARMACEUTICAL COMPOSITION CONTAINING BICYCLIC TYPE COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 1994-06-23 | — | — | WO | claimed |
| US-20100099752-A1 | PHARMACEUTICAL COMPOSITION CONTAINING BICYCLIC TYPE COMPOUNDS | SMITHKLINE BEECHAM PLC. (GB) | 2010-04-22 | — | — | US | disclosed |
| US-20070088064-A1 | PHARMACEUTICAL COMPOSITION CONTAINING BICYCLIC TYPE COMPOUNDS | SMITHKLINE BEECHAM PLC | 2007-04-19 | — | — | US | disclosed |
| US-20030236410-A1 | Pharmaceutical composition containing bicyclic type compounds | SMITHKLINE BEECHAM P.L.C. | 2003-12-25 | — | — | US | disclosed |
| US-20020123630-A1 | Pharmaceutical composition containing bicyclic type compounds | SMITHKLINE BEECHAM P.L.C. | 2002-09-05 | — | — | US | disclosed |
| US-20010021780-A1 | Pharmaceutical composition containing bicyclic type compounds | SMITHKLINE BEECHAM P.L.C. | 2001-09-13 | — | — | US | disclosed |
| EP-0673374-B1 | PHARMACEUTICAL COMPOSITION CONTAINING BICYCLIC TYPE COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 2000-03-01 | — | — | EP | disclosed |
| US-5948811-A | Pharmaceutical composition containing bicyclic type compounds | SMITHKLINE BEEGHAM P.L.C. (GB) | 1999-09-07 | — | — | US | disclosed |
| EP-0673374-A1 | PHARMACEUTICAL COMPOSITION CONTAINING BICYCLIC TYPE COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 1995-09-27 | — | — | EP | disclosed |
| WO-1994013657-A1 | PHARMACEUTICAL COMPOSITION CONTAINING BICYCLIC TYPE COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 1994-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236410-A1 | Pharmaceutical composition containing bicyclic type compounds | CLIC1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CYP2B6 | ABCC9 162/4885ABCB1 132/4885KDM4E 3793/4885 |
| US-20070088064-A1 | PHARMACEUTICAL COMPOSITION CONTAINING BICYCLIC TYPE COMPOUNDS | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CFH, CBR3 | ABCC9 155/4885ABCB1 104/4885KDM4E 4277/4885 |
| US-20010021780-A1 | Pharmaceutical composition containing bicyclic type compounds | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CLIC1, NAF1 | ABCC9 122/4885ABCB1 126/4885KDM4E 4139/4885 |
| US-20100099752-A1 | PHARMACEUTICAL COMPOSITION CONTAINING BICYCLIC TYPE COMPOUNDS | SNCA, GRIN2C, PYGB | ABCC9 1314/4885ABCB1 595/4885KDM4E 4382/4885 |
| US-20020123630-A1 | Pharmaceutical composition containing bicyclic type compounds | CLIC1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CFH | ABCC9 111/4885ABCB1 136/4885KDM4E 3976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.