Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.62 |
| ▸ | BCHE | P06276 | 4/20 | 0.61 |
| ▸ | ACHE | P22303 | 4/20 | 0.61 |
| ▸ | BACE1 | P56817 | 4/20 | 0.61 |
| ▸ | HRH1 | P35367 | 1/20 | 0.60 |
| ▸ | CCR6 | P51684 | 1/20 | 0.57 |
| ▸ | NPY2R | P49146 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | DRD4 | P21917 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7473216 | 0.99 | KCNH2 (0.60) | KCNH2BCHEACHEBACE1HRH1 | |
| SCHEMBL8791275 | 0.93 | KCNH2 (0.60) | KCNH2BCHEACHEBACE1HRH1 | |
| SCHEMBL8190619 | 0.88 | KCNH2 (0.53) | KCNH2BCHEACHEBACE1HRH1 | |
| SCHEMBL7472985 | 0.88 | LMNA (0.56) | KCNH2BCHEACHEBACE1HRH1 | |
| SCHEMBL8948483 | 0.86 | KCNH2 (0.51) | KCNH2BCHEACHEBACE1HRH1 | |
| SCHEMBL8792369 | 0.86 | TSHR (0.55) | KCNH2BCHEACHEBACE1HRH1 | |
| SCHEMBL8948348 | 0.85 | HRH1 (0.52) | KCNH2BCHEACHEBACE1HRH1 | |
| SCHEMBL3824647 | 0.85 | BCHE (0.51) | KCNH2BCHEACHEBACE1HRH1 | |
| SCHEMBL8792733 | 0.85 | KCNH2 (0.50) | KCNH2BCHEACHEBACE1HRH1 | |
| SCHEMBL9873080 | 0.85 | HRH1 (0.67) | KCNH2ACHEBACE1HRH1NPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0844825-B1 | INSECTICIDAL N-(SUBSTITUTED ARYLMETHYL)-4- BIS(SUBSTITUTED PHENYL OR PYRIDYL)METHYL]PIPERIDINES | FMC CORP (US) | 2002-11-27 | — | — | EP | disclosed |
| US-6214845-B1 | AGRICULTURE | FMC CORPORATION | 2001-04-10 | — | — | US | disclosed |
| US-6184234-B1 | EFFECTIVE AGRICULTURAL PESTICIDE FOR TOBACCO, BEETS, BEANS, CABBAGE CROPS | FMC CORPORATION | 2001-02-06 | — | — | US | disclosed |
| EP-0844825-A4 | INSECTICIDAL N-(SUBSTITUTED ARYLMETHYL)-4- BIS(SUBSTITUTED PHENYL OR PYRIDYL)METHYL]PIPERIDINES | FMC CORP (US) | 2000-04-05 | — | — | EP | disclosed |
| US-6030987-A | Insecticidal N-(substituted arylmethyl)-4-[bis(substituted phenyl or pyridyl)methyl]piperidines | FMC CORPORATION (US) | 2000-02-29 | — | — | US | disclosed |
| US-6017931-A | Insecticidal compositions containing n-(substituted phenylmethyl)-4-[bis(substituted phenyl)methyl]piperidines | FMC CORPORATION | 2000-01-25 | — | — | US | disclosed |
| EP-0844825-A1 | INSECTICIDAL N-(SUBSTITUTED ARYLMETHYL)-4- BIS(SUBSTITUTED PHENYL OR PYRIDYL)METHYL]PIPERIDINES | FMC CORPORATION (US) | 1998-06-03 | — | — | EP | disclosed |
| EP-0748159-A4 | INSECTICIDAL N-(SUBSTITUTED ARYLMETHYL)-4- BIS(SUBSTITUTED PHENYL)METHYL]PIPERIDINES | FMC CORP (US) | 1997-11-19 | — | — | EP | disclosed |
| US-5639763-A | FOR AGRICULTURAL APPLICATIONS | FMC CORPORATION (US) | 1997-06-17 | — | — | US | disclosed |
| EP-0748159-A1 | INSECTICIDAL N-(SUBSTITUTED ARYLMETHYL)-4- BIS(SUBSTITUTED PHENYL)METHYL]PIPERIDINES | FMC CORPORATION (US) | 1996-12-18 | — | — | EP | disclosed |
| WO-1996036228-A1 | INSECTICIDAL N-(SUBSTITUTED ARYLMETHYL)-4-[BIS(SUBSTITUTED PHENYL OR PYRIDYL)METHYL]PIPERIDINES | FMC CORPORATION (US) | 1996-11-21 | — | — | WO | disclosed |
| US-5569664-A | AGRICULTURAL INSECTICIDES | FMC CORPORATION (US) | 1996-10-29 | — | — | US | disclosed |
| WO-1995023507-A1 | INSECTICIDAL N-(SUBSTITUTED ARYLMETHYL)-4-[BIS(SUBSTITUTED PHENYL)METHYL]PIPERIDINES | FMC CORPORATION (US) | 1995-09-08 | — | — | WO | disclosed |