Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MLYCD | O95822 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL320697 | 0.89 | KMT2A (0.60) | KMT2AMEN1LMNAGAASMN1; SMN2 | |
| SCHEMBL321631 | 0.88 | HIF1A (0.65) | KMT2AMEN1LMNAGAASMN1; SMN2 | |
| SCHEMBL7477445 | 0.81 | F10 (0.71) | KMT2AMEN1LMNASMN1; SMN2MAPT | |
| SCHEMBL321736 | 0.80 | KMT2A (0.58) | KMT2AMEN1GAAMAPTNPC1 | |
| SCHEMBL2953316 | 0.79 | HIF1A (0.73) | KMT2AMEN1GAASMN1; SMN2MAPT | |
| SCHEMBL321291 | 0.79 | ALDH1A1 (0.63) | KMT2AMEN1LMNAGAASMN1; SMN2 | |
| SCHEMBL6809487 | 0.78 | GAA (0.62) | LMNAGAASMN1; SMN2MAPK1KCNH2 | |
| SCHEMBL6809507 | 0.78 | SMN1; SMN2 (0.73) | KMT2ALMNAGAASMN1; SMN2MAPK1 | |
| SCHEMBL18328476 | 0.78 | GAA (0.61) | KMT2AMEN1LMNAGAASMN1; SMN2 | |
| SCHEMBL3898629 | 0.78 | CYP1A2 (0.59) | KMT2AMEN1SMN1; SMN2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183235-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000071510-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2000-11-30 | — | — | WO | disclosed |