Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | SDCBP | O00560 | 2/20 | 0.55 |
| ▸ | SDC2 | P34741 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL714953 | 0.81 | FFAR1 (0.61) | KMT2ARAB9ASMN1; SMN2HSD17B10MEN1 | |
| SCHEMBL1251803 | 0.79 | PKM (0.56) | HPGDSDCBPSDC2KMT2ARAB9A | |
| SCHEMBL13100952 | 0.78 | LMNA (0.48) | HPGDHSD17B10ALDH1A1HTTKDM4E | |
| SCHEMBL9035361 | 0.76 | HPGD (0.57) | HPGDSDCBPSDC2KMT2ARAB9A | |
| SCHEMBL1286277 | 0.76 | FFAR1 (0.65) | HPGDSDCBPSDC2KMT2ARAB9A | |
| SCHEMBL3927340 | 0.76 | HPGD (0.53) | HPGDSDCBPSDC2KMT2ARAB9A | |
| SCHEMBL1395735 | 0.75 | SMN1; SMN2 (0.66) | HPGDSDCBPSDC2KMT2ARAB9A | |
| SCHEMBL11218295 | 0.75 | KMT2A (0.54) | HPGDSDCBPSDC2KMT2ARAB9A | |
| Hydrochloric Acid SCHEMBL11623652 | 0.75 | FFAR1 (0.63) | HPGDSDCBPSDC2KMT2ARAB9A | |
| SCHEMBL10633574 | 0.74 | HPGD (0.51) | HPGDSDCBPSDC2KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1228066-A2 | SULFONAMIDE DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001032646-A2 | SULFONAMIDE DERIVATIVES | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-05-10 | — | — | WO | disclosed |