Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | UBE2N | P61088 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 3/20 | 0.45 |
| ▸ | ADK | P55263 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469541 | 0.92 | KMT2A (0.57) | KMT2AMEN1TSHRUBE2NTDP1 | |
| SCHEMBL7476860 | 0.86 | TSHR (0.64) | KMT2AMEN1TSHRNPSR1USP2 | |
| SCHEMBL7473140 | 0.86 | TSHR (0.50) | KMT2AMEN1TSHRNPSR1USP2 | |
| SCHEMBL7470492 | 0.86 | TSHR (0.53) | KMT2AMEN1TSHRNPSR1USP2 | |
| SCHEMBL7465749 | 0.84 | GSK3B (0.48) | KMT2AMEN1TSHRUBE2NTDP1 | |
| SCHEMBL7465025 | 0.83 | TSHR (0.55) | KMT2AMEN1TSHRNPSR1USP2 | |
| SCHEMBL7476552 | 0.82 | GSK3B (0.54) | KMT2AMEN1TSHRNPSR1USP2 | |
| SCHEMBL7472270 | 0.82 | ALDH1A1 (0.55) | KMT2AMEN1TSHRTDP1NPSR1 | |
| SCHEMBL7472445 | 0.81 | TSHR (0.51) | KMT2AMEN1TSHRNPSR1USP2 | |
| SCHEMBL7476998 | 0.81 | TSHR (0.52) | KMT2AMEN1TSHRNPSR1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-B1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO MCNEIL PHARM INC (US) | 2002-12-18 | — | — | EP | disclosed |
| US-5854242-A | Benzoxazine antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |