Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | ADK | P55263 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472920 | 0.92 | TSHR (0.56) | TSHRALDH1A1SMN1; SMN2HTTMEN1 | |
| SCHEMBL7473291 | 0.91 | TSHR (0.54) | TSHRALDH1A1SMN1; SMN2HTTMEN1 | |
| SCHEMBL7472305 | 0.90 | TSHR (0.53) | TSHRALDH1A1SMN1; SMN2HTTMEN1 | |
| SCHEMBL7471315 | 0.90 | ALDH1A1 (0.68) | TSHRALDH1A1SMN1; SMN2HTTMEN1 | |
| SCHEMBL7470492 | 0.89 | TSHR (0.53) | TSHRALDH1A1SMN1; SMN2HTTMEN1 | |
| SCHEMBL7476998 | 0.89 | TSHR (0.52) | TSHRALDH1A1SMN1; SMN2HTTMEN1 | |
| SCHEMBL7473140 | 0.86 | TSHR (0.50) | TSHRALDH1A1SMN1; SMN2HTTMEN1 | |
| SCHEMBL7467559 | 0.86 | TSHR (0.58) | TSHRALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL7477205 | 0.86 | KMT2A (0.67) | TSHRALDH1A1SMN1; SMN2HTTMEN1 | |
| SCHEMBL7473595 | 0.85 | SIRT2 (0.50) | TSHRALDH1A1SMN1; SMN2HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-B1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO MCNEIL PHARM INC (US) | 2002-12-18 | — | — | EP | disclosed |
| US-5854242-A | Benzoxazine antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |