Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.56 |
| ▸ | PDE4A | P27815 | 8/20 | 0.56 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TPH1 | P17752 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7088472 | 0.85 | PDE4B (0.65) | RECQLPDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7417873 | 0.83 | PDE4B (0.62) | RECQLPDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7091205 | 0.81 | PDE4B (0.57) | RECQLPDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7324348 | 0.81 | PDE4B (0.56) | PDE4BPDE4DPDE4APDE4CMEN1 | |
| SCHEMBL13317191 | 0.80 | RECQL (0.61) | RECQLPDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7026447 | 0.80 | PDE4B (0.58) | RECQLPDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7332617 | 0.80 | PDE4B (0.58) | RECQLPDE4BPDE4DPDE4APDE4C | |
| Bicarbonate SCHEMBL7091204 | 0.80 | CSNK2A1 (0.58) | PDE4BPDE4DPDE4APDE4CPOLB | |
| SCHEMBL2371289 | 0.78 | PDE4B (0.60) | RECQLPDE4BPDE4DPDE4APDE4C | |
| SCHEMBL8571660 | 0.78 | KMT2A (0.61) | RECQLPDE4BPDE4DPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998056756-A1 | CATECHOL AMINO ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CHEIL JEDANG CORPORATION (KR) | 1998-12-17 | — | — | WO | claimed |
| WO-1998056756-A1 | CATECHOL AMINO ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CHEIL JEDANG CORPORATION (KR) | 1998-12-17 | — | — | WO | disclosed |