Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.44 |
| ▸ | F2R | P25116 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17953060 | 0.84 | FFAR4 (0.35) | EPHX1EPHX2ITGB3ITGA2BF2R | |
| SCHEMBL29223350 | 0.82 | ITGB3 (0.44) | ITGB3ITGA2BF2RCHRM2CHRM1 | |
| SCHEMBL1652121 | 0.81 | EPHX1 (0.47) | EPHX1EPHX2KDM1ARIPK1 | |
| SCHEMBL4599331 | 0.81 | ITGB3 (0.49) | ITGB3ITGA2BF2RMEN1KMT2A | |
| SCHEMBL14330457 | 0.80 | EPHX1 (0.46) | EPHX1EPHX2KDM1A | |
| SCHEMBL4577744 | 0.79 | EPHX1 (0.48) | EPHX1EPHX2KDM1ACHRM2CHRM1 | |
| SCHEMBL4577748 | 0.79 | EPHX1 (0.48) | EPHX1EPHX2KDM1ARIPK1 | |
| SCHEMBL13754851 | 0.78 | EPHX1 (0.47) | EPHX1EPHX2KDM1ARIPK1 | |
| SCHEMBL16095553 | 0.78 | EPHX1 (0.47) | EPHX1EPHX2KDM1ACHRM2CHRM1 | |
| SCHEMBL3036073 | 0.78 | ITGB3 (0.46) | EPHX1EPHX2ITGB3ITGA2BF2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227090-A1 | AMINE DERIVATIVES | Tadeka Chemical Industries, Ltd. (JP) | 2002-07-31 | — | — | EP | disclosed |