Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.49 |
| ▸ | F2R | P25116 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3036073 | 0.84 | ITGB3 (0.46) | ITGB3ITGA2BF2RMEN1KMT2A | |
| SCHEMBL30684623 | 0.84 | ITGB3 (0.46) | ITGB3ITGA2BF2RMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4513407 | 0.82 | ITGB3 (0.45) | ITGB3ITGA2BF2RMEN1KMT2A | |
| SCHEMBL6222860 | 0.81 | TPSAB1 (0.55) | ITGB3ITGA2BF2RMEN1KMT2A | |
| SCHEMBL29223350 | 0.81 | ITGB3 (0.44) | ITGB3ITGA2BF2RMEN1KMT2A | |
| SCHEMBL7477572 | 0.81 | EPHX1 (0.45) | ITGB3ITGA2BF2RMEN1KMT2A | |
| SCHEMBL17626803 | 0.81 | ITGB3 (0.39) | ITGB3ITGA2BMEN1KMT2AGNAI3 | |
| SCHEMBL785724 | 0.81 | AKR1C3 (0.43) | ITGB3ITGA2BMEN1KMT2AGNAI3 | |
| Acetic Acid SCHEMBL1773420 | 0.81 | TPSAB1 (0.42) | ITGB3ITGA2BF2RMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11079847 | 0.80 | TPSAB1 (0.53) | ITGB3ITGA2BF2RMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1759118-B | Diazepinoindole derivatives as kinase inhibitors | PFIZER | 2010-12-08 | — | — | CN | disclosed |
| EP-1910290-A2 | GPCR AGONISTS | Prosidion Limited (GB) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007003962-A2 | GPCR AGONISTS | PROSIDION LIMITED (GB) | 2007-01-11 | — | — | WO | disclosed |
| CN-1759118-A | Diazepinoindole derivatives as kinase inhibitors | PFIZER (US) | 2006-04-12 | — | — | CN | disclosed |