Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.47 |
| ▸ | ITGAV | P06756 | 6/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7390822 | 0.85 | ITGB1 (0.45) | ITGB1ITGA4SMN1; SMN2MAPT | |
| SCHEMBL7648050 | 0.85 | ITGB1 (0.45) | ITGB1ITGA4SMN1; SMN2MAPT | |
| SCHEMBL5700977 | 0.84 | ITGB1 (0.68) | ITGB3ITGAVITGB1ITGA4KMT2A | |
| SCHEMBL5700988 | 0.84 | ITGB1 (0.68) | ITGB3ITGAVITGB1ITGA4KMT2A | |
| SCHEMBL7531775 | 0.83 | ITGB1 (0.44) | ITGB3ITGAVITGB1ITGA4KMT2A | |
| SCHEMBL5700989 | 0.82 | ITGB1 (0.51) | ITGB1ITGA4MAPTKMT2A | |
| SCHEMBL5700984 | 0.82 | ITGB1 (0.51) | ITGB1ITGA4MAPTKMT2A | |
| Trifluoroacetic Acid SCHEMBL5701085 | 0.82 | ITGB1 (0.42) | ITGB1ITGA4SMN1; SMN2MAPT | |
| SCHEMBL5700996 | 0.82 | ITGB1 (0.51) | ITGB1ITGA4MAPTKMT2A | |
| SCHEMBL5700993 | 0.82 | ITGB1 (0.51) | ITGB1ITGA4MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |
| EP-1027328-A1 | SUBSTITUTED ANILIDES | Aventis Pharma Limited (GB) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999023063-A1 | SUBSTITUTED ANILIDES | AVENTIS PHARMA LIMITED (GB) | 1999-05-14 | — | — | WO | disclosed |