Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7479179 | 0.90 | KMT2A (0.43) | ALDH1A1KMT2ATLR9ATMKDM4E | |
| SCHEMBL7477004 | 0.82 | KDM4E (0.51) | ALDH1A1KMT2AKDM4ENPC1HTT | |
| SCHEMBL2326728 | 0.74 | ALDH1A1 (0.70) | ALDH1A1KMT2ATLR9ATMKDM4E | |
| SCHEMBL31474854 | 0.72 | ALDH1A1 (0.64) | ALDH1A1KMT2ATLR9ATMKDM4E | |
| SCHEMBL3158636 | 0.72 | ALDH1A1 (0.67) | ALDH1A1KMT2ATLR9ATMKDM4E | |
| SCHEMBL7479438 | 0.70 | CSNK1A1 (0.40) | ALDH1A1KMT2AKDM4ENPC1HTT | |
| SCHEMBL11441705 | 0.70 | ALDH1A1 (0.68) | ALDH1A1KMT2AKDM4ENPC1L3MBTL1 | |
| SCHEMBL7480580 | 0.67 | CSNK1A1 (0.39) | ALDH1A1KDM4ENPC1HTTMAPT | |
| SCHEMBL2329961 | 0.66 | ALDH1A1 (0.58) | ALDH1A1KMT2AL3MBTL1MAPTRAB9A | |
| SCHEMBL614951 | 0.66 | ALDH1A1 (1.00) | ALDH1A1KMT2AKDM4ENPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883622-B1 | PROTON PUMP INHIBITOR | APOTEX INC (CA) | 2002-05-15 | — | — | EP | claimed |
| US-6093738-A | IMIDAZO(1,2-D)-THIADIAZOLE COMPOUNDS; PEPTIC ULCER TREATMENT | KARIMIAN KHASHAYAR (CA) | 2000-07-25 | — | — | US | claimed |
| CN-1216527-A | Method for scavenging mercaptan | APOTEX INC (CA) | 1999-05-12 | — | — | CN | claimed |
| EP-0883622-B1 | PROTON PUMP INHIBITOR | APOTEX INC (CA) | 2002-05-15 | — | — | EP | disclosed |