Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | TYMS | P04818 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PDE6D | O43924 | 1/20 | 0.44 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7479179 | 0.83 | KMT2A (0.43) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL7477705 | 0.82 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL7474969 | 0.80 | DRD2 (0.54) | KDM4EALDH1A1HPGDMAOAHSD17B10 | |
| SCHEMBL8044065 | 0.79 | HSD17B10 (0.47) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL7473909 | 0.78 | CTSD (0.47) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL7480580 | 0.76 | CSNK1A1 (0.39) | KDM4EALDH1A1HPGDHSD17B10ESR2 | |
| SCHEMBL7475534 | 0.76 | SMN1; SMN2 (0.47) | KDM4EALDH1A1HPGDTYMSHSD17B10 | |
| SCHEMBL7474031 | 0.76 | DYRK1A (0.51) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL7007238 | 0.76 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL7470768 | 0.76 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883622-B1 | PROTON PUMP INHIBITOR | APOTEX INC (CA) | 2002-05-15 | — | — | EP | claimed |
| US-6093738-A | IMIDAZO(1,2-D)-THIADIAZOLE COMPOUNDS; PEPTIC ULCER TREATMENT | KARIMIAN KHASHAYAR (CA) | 2000-07-25 | — | — | US | claimed |
| CN-1216527-A | Method for scavenging mercaptan | APOTEX INC (CA) | 1999-05-12 | — | — | CN | claimed |
| EP-0883622-B1 | PROTON PUMP INHIBITOR | APOTEX INC (CA) | 2002-05-15 | — | — | EP | disclosed |