Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7482806 | 0.91 | LMNA (0.54) | MAPTKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL7482289 | 0.90 | KDM4E (0.65) | MAPTKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL7476977 | 0.90 | KDM4E (0.53) | MAPTKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL7472611 | 0.89 | MAPT (0.53) | MAPTKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL7480913 | 0.88 | MAPT (0.52) | MAPTKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL7486615 | 0.88 | KDM4E (0.53) | MAPTKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL7479813 | 0.87 | MAPT (0.53) | MAPTKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL7481904 | 0.86 | MAPT (0.56) | MAPTKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL7483473 | 0.86 | KDM4E (0.57) | MAPTKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL7486681 | 0.85 | MAPT (0.74) | MAPTKDM4EHSD17B10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229010-A1 | NOVEL DIARYLAMIDE DERIVATIVES AND USE THEREOF AS MEDICINES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |