Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 8/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7476977 | 0.91 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10NPSR1 | |
| SCHEMBL7477799 | 0.90 | MAPT (0.53) | KDM4EALDH1A1HPGDHSD17B10NPSR1 | |
| SCHEMBL7472611 | 0.90 | MAPT (0.53) | KDM4EALDH1A1HPGDHSD17B10NPSR1 | |
| SCHEMBL7476164 | 0.90 | KDM4E (0.63) | KDM4EALDH1A1HPGDHSD17B10NPSR1 | |
| SCHEMBL7482806 | 0.90 | LMNA (0.54) | KDM4EALDH1A1HPGDHSD17B10NPSR1 | |
| SCHEMBL7481904 | 0.90 | MAPT (0.56) | KDM4EALDH1A1HPGDHSD17B10NPSR1 | |
| SCHEMBL7480913 | 0.89 | MAPT (0.52) | KDM4EALDH1A1HPGDHSD17B10NPSR1 | |
| SCHEMBL7479629 | 0.88 | MAPT (0.59) | KDM4EALDH1A1HPGDHSD17B10NPSR1 | |
| SCHEMBL7481989 | 0.88 | KDM4E (0.63) | KDM4EALDH1A1HPGDHSD17B10NPSR1 | |
| SCHEMBL7483473 | 0.87 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229010-A1 | NOVEL DIARYLAMIDE DERIVATIVES AND USE THEREOF AS MEDICINES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |