Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470112 | 0.93 | HDAC1 (0.43) | HDAC1HDAC6ALDH1A1TP53SCN9A | |
| SCHEMBL7466211 | 0.92 | HDAC1 (0.45) | HDAC1HDAC6ALDH1A1TP53SCN9A | |
| SCHEMBL7472348 | 0.86 | TP53 (0.44) | HDAC1HDAC6ALDH1A1TP53SCN9A | |
| SCHEMBL8589807 | 0.80 | ALDH1A1 (0.38) | ALDH1A1TP53SCN9AMAPT | |
| SCHEMBL7469133 | 0.77 | HDAC1 (0.49) | HDAC1HDAC6ALDH1A1TP53SCN9A | |
| SCHEMBL7470885 | 0.77 | HDAC1 (0.46) | HDAC1HDAC6ALDH1A1TP53SCN9A | |
| SCHEMBL9217957 | 0.73 | MAPK8 (0.37) | NPC1RAB9AATMDGAT2 | |
| SCHEMBL7471458 | 0.71 | OXTR (0.42) | TP53SCN9AMAPTPTGDR2 | |
| SCHEMBL7476645 | 0.70 | MAPT (0.42) | TP53SCN9AMAPTHDAC8PTGDR2 | |
| SCHEMBL7463750 | 0.70 | HDAC1 (0.45) | HDAC1HDAC6ALDH1A1TP53SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687251-B1 | 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS | SANOFI SYNTHELABO (FR) | 2002-02-27 | — | — | EP | disclosed |
| WO-1995018105-A1 | 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS | SANOFI (FR) | 1995-07-06 | — | — | WO | disclosed |