Sugi Predict

Sugi Predict / Compounds / SCHEMBL7477923

SCHEMBL7477923

SCHEMBL7477923

CCCCc1nc(SC)c(C(=O)CC(=O)OCC)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)NCc2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ AGTR2 P50052 6/20 0.82
▸ AGTR1 P30556 3/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8348141 0.90 AGTR2 (1.00) AGTR2AGTR1
SCHEMBL7485475 0.89 AGTR2 (1.00) AGTR2AGTR1
SCHEMBL7539987 0.88 AGTR2 (0.82) AGTR2AGTR1
SCHEMBL8348415 0.86 AGTR2 (0.89) AGTR2AGTR1
SCHEMBL8347250 0.86 AGTR2 (0.91) AGTR2AGTR1
SCHEMBL6544946 0.85 AGTR2 (1.00) AGTR2AGTR1
SCHEMBL7480189 0.85 AGTR2 (0.78) AGTR2AGTR1
SCHEMBL8898987 0.85 AGTR2 (0.83) AGTR2AGTR1
SCHEMBL8976602 0.83 AGTR2 (1.00) AGTR2AGTR1
SCHEMBL7701057 0.83 AGTR2 (1.00) AGTR2AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0748314-B1 TETRASUBSTITUTED IMIDAZOLE DERIVATIVES, METHOD FOR PREPARING THE SAME, USE THEREOF AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AVENTIS PHARMA SA (FR) 2002-05-15 — — EP claimed