Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469569 | 0.85 | UGT2B7 (0.52) | UGT2B7SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL6839913 | 0.85 | UGT2B7 (0.52) | UGT2B7SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL5716820 | 0.82 | UGT2B7 (0.53) | UGT2B7EPHX1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7440695 | 0.81 | CES2 (0.53) | UGT2B7SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL8120372 | 0.79 | UGT2B7 (0.50) | UGT2B7EPHX1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1137612 | 0.78 | UGT2B7 (0.58) | UGT2B7EPHX1MMP9 | |
| SCHEMBL29941609 | 0.78 | UGT2B7 (0.58) | UGT2B7EPHX1MMP9 | |
| SCHEMBL7336112 | 0.77 | SLC6A3 (0.50) | UGT2B7SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL27175927 | 0.77 | CES2 (0.48) | EPHX1CES2CES1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5969924 | 0.76 | UGT2B7 (0.56) | UGT2B7EPHX1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077701-A4 | ANTI-VIRAL COMPOUNDS | LILLY CO ELI (US) | 2002-03-20 | — | — | EP | disclosed |
| US-6358971-B1 | FOR INHIBITING THE GROWTH OF A PICORNAVIRUS | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |
| CN-1292697-A | Anti-viral compound | LILLY CO ELI (US) | 2001-04-25 | — | — | CN | disclosed |
| EP-1077701-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999059587-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1999-11-25 | — | — | WO | disclosed |