Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 6/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 5/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475251 | 0.92 | HSD17B10 (0.40) | KMT2AMEN1MAPTMAPK1CA2 | |
| SCHEMBL7468810 | 0.87 | BRD4 (0.38) | KMT2AMEN1MAPTBRD4CREBBP | |
| SCHEMBL7468474 | 0.86 | BRD4 (0.35) | BRD4MAOB | |
| SCHEMBL7471024 | 0.83 | KMT2A (0.45) | KMT2AMEN1MAPTMAPK1BRD4 | |
| SCHEMBL7472405 | 0.83 | PARP1 (0.45) | KMT2AMEN1MAPTMAPK1BRD4 | |
| SCHEMBL7470575 | 0.81 | USP2 (0.45) | KMT2AMEN1MAPTBRD4CREBBP | |
| SCHEMBL7463447 | 0.80 | HSD17B10 (0.41) | MAPK1HSD17B10TP53ALDH1A1 | |
| SCHEMBL7472656 | 0.80 | USP2 (0.33) | MAPK1HSD17B10 | |
| SCHEMBL7464298 | 0.78 | ACE2 (0.35) | KMT2AMEN1MAPTHSD17B10TP53 | |
| SCHEMBL7476297 | 0.78 | ALOX5 (0.42) | KMT2AMEN1MAPTHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-B1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO MCNEIL PHARM INC (US) | 2002-12-18 | — | — | EP | disclosed |
| US-5854242-A | Benzoxazine antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |