Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 17/20 | 0.46 |
| ▸ | CTSL | P07711 | 8/20 | 0.44 |
| ▸ | CTSS | P25774 | 7/20 | 0.44 |
| ▸ | CTSB | P07858 | 3/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5850136 | 0.86 | CTSK (0.52) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL5848116 | 0.77 | CTSK (0.52) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL5848122 | 0.76 | CTSK (0.51) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL5848350 | 0.76 | CTSK (0.51) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL5848519 | 0.75 | CTSK (0.48) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL5849048 | 0.74 | CTSK (0.49) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL5848999 | 0.74 | CTSK (0.49) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL5848463 | 0.74 | CTSK (0.49) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL6374276 | 0.74 | CTSB (0.41) | CTSKCTSLCTSSCTSB | |
| SCHEMBL5850145 | 0.74 | CTSK (0.48) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254898-A1 | BENZENE-FUSED HETEROCYCLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-11-06 | — | — | EP | claimed |