Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | EDNRA | P25101 | 3/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8829420 | 0.86 | RAB9A (0.62) | RAB9AKMT2AMEN1EDNRAMAPK9 | |
| SCHEMBL20217881 | 0.86 | RAB9A (0.62) | RAB9AKMT2AMEN1EDNRAMAPK9 | |
| SCHEMBL8828117 | 0.79 | KMT2A (0.55) | RAB9AKMT2AMEN1EDNRAMAPK9 | |
| SCHEMBL15238894 | 0.79 | KMT2A (0.55) | RAB9AKMT2AMEN1EDNRAMAPK9 | |
| SCHEMBL5045046 | 0.79 | KMT2A (0.55) | RAB9AKMT2AMEN1EDNRAMAPK9 | |
| SCHEMBL4846856 | 0.79 | RAB9A (0.55) | RAB9AKMT2AMEN1EDNRAHPGD | |
| SCHEMBL14261990 | 0.78 | RAB9A (0.59) | RAB9AKMT2AMEN1HPGDSMN1; SMN2 | |
| SCHEMBL2555520 | 0.77 | KMT2A (0.55) | RAB9AKMT2AMEN1EDNRAMAPK9 | |
| SCHEMBL7482561 | 0.76 | RAB9A (0.57) | RAB9AKMT2AMEN1HPGDSMN1; SMN2 | |
| SCHEMBL7446886 | 0.76 | RAB9A (0.49) | RAB9AKMT2AMEN1EDNRAMAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133484-A2 | HETEROCYCLIC DERIVATIVES AND THEIR USE AS INTEGRIN INHIBITORS | AstraZeneca AB (SE) | 2001-09-19 | — | — | EP | disclosed |
| WO-2000005223-A2 | HETEROCYCLIC DERIVATIVES AND THEIR USE AS INTEGRIN INHIBITORS | ASTRAZENECA AB (SE) | 2000-02-03 | — | — | WO | disclosed |