Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TAS1R3 | Q7RTX0 | 7/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 7/20 | 0.54 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14262002 | 0.87 | GAA (0.67) | GAASMN1; SMN2TAS1R3TAS1R1UTS2R | |
| SCHEMBL8829420 | 0.81 | RAB9A (0.62) | RAB9AGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL20217881 | 0.81 | RAB9A (0.62) | RAB9AGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL14261991 | 0.81 | GAA (0.62) | RAB9AGAASMN1; SMN2KMT2ATAS1R3 | |
| SCHEMBL14707654 | 0.80 | GAA (0.50) | RAB9AGAASMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL14261914 | 0.79 | RAB9A (0.55) | RAB9AGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL14261917 | 0.79 | RAB9A (0.56) | RAB9AGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7478628 | 0.78 | RAB9A (0.59) | RAB9AGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL14262004 | 0.77 | GAA (0.72) | RAB9AGAASMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL14261915 | 0.77 | RAB9A (0.47) | RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7348357-B2 | bactericide; derivatives of pseudopeptide Andrimid in which beta-phenylalanine amide is replaced by heteroaromatic or substituted aromatic amide; N-{(1S)-3-[((1S)-1-{[(3R,4S)-1,4-Dimethyl-2,5-dioxo-3-pyrrolidinyl]carbonyl}-2-methylpropyl)amino]-3-oxo-1-phenylpropyl}-2-pyridinecarboxamide; antibiotics | BAYER HEALTHCARE AG (DE) | 2008-03-25 | — | — | US | disclosed |
| US-7348357-B2 | bactericide; derivatives of pseudopeptide Andrimid in which beta-phenylalanine amide is replaced by heteroaromatic or substituted aromatic amide; N-{(1S)-3-[((1S)-1-{[(3R,4S)-1,4-Dimethyl-2,5-dioxo-3-pyrrolidinyl]carbonyl}-2-methylpropyl)amino]-3-oxo-1-phenylpropyl}-2-pyridinecarboxamide; antibiotics | BAYER HEALTHCARE AG (DE) | 2008-03-25 | — | — | US | disclosed |