Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7478645 | 0.81 | TP53 (0.53) | TP53POLB | |
| SCHEMBL3762079 | 0.80 | TP53 (0.56) | TP53POLB | |
| Hydrochloric Acid SCHEMBL31186624 | 0.78 | TP53 (0.54) | TP53POLB | |
| SCHEMBL8365982 | 0.77 | AKR1C3 (0.46) | TP53AKR1C3POLBHCRTR1HCRTR2 | |
| SCHEMBL3345264 | 0.76 | POLB (0.39) | TP53POLB | |
| SCHEMBL1651679 | 0.76 | POLB (0.39) | TP53POLB | |
| SCHEMBL6970610 | 0.74 | MEN1 (0.54) | — | |
| SCHEMBL14941549 | 0.73 | L3MBTL1 (0.62) | POLB | |
| SCHEMBL4780628 | 0.73 | S1PR1 (0.43) | TP53CYP2C19 | |
| SCHEMBL8602693 | 0.73 | S1PR1 (0.43) | TP53CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933361-B1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO CO LTD (JP) | 2002-03-27 | — | — | EP | disclosed |