Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 6/20 | 0.58 |
| ▸ | CES2 | O00748 | 5/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8974843 | 0.85 | PDE2A (0.60) | PDE2ACES2CES1KDM4EALDH1A1 | |
| SCHEMBL8974847 | 0.85 | PDE2A (0.60) | PDE2ACES2CES1KDM4EALDH1A1 | |
| SCHEMBL20474139 | 0.82 | PDE2A (0.61) | PDE2AKIF11EPHX1GAA | |
| SCHEMBL7477905 | 0.82 | PDE2A (0.53) | PDE2ACES2KIF11KDM4EALDH1A1 | |
| SCHEMBL2738655 | 0.80 | PDE2A (0.51) | PDE2ACES2KIF11KDM4EALDH1A1 | |
| SCHEMBL29658770 | 0.79 | CES2 (0.64) | CES2CES1ALDH1A1IDO1KCNN4 | |
| SCHEMBL5348191 | 0.79 | CES2 (0.64) | CES2CES1ALDH1A1IDO1KCNN4 | |
| SCHEMBL18172071 | 0.78 | PDE2A (0.49) | PDE2ACES2KIF11KDM4EALDH1A1 | |
| SCHEMBL20791346 | 0.77 | PDE2A (0.54) | PDE2AKIF11KDM4EALDH1A1HPGD | |
| SCHEMBL30525047 | 0.77 | PDE2A (0.54) | PDE2AKIF11KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077701-A4 | ANTI-VIRAL COMPOUNDS | LILLY CO ELI (US) | 2002-03-20 | — | — | EP | disclosed |
| US-6358971-B1 | FOR INHIBITING THE GROWTH OF A PICORNAVIRUS | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |
| EP-1077701-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999059587-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1999-11-25 | — | — | WO | disclosed |