Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474131 | 0.84 | CNR2 (0.38) | CRHR1CNR2 | |
| SCHEMBL7475280 | 0.80 | MCHR1 (0.39) | CRHR1 | |
| SCHEMBL5409624 | 0.80 | CRHR1 (0.55) | CRHR1 | |
| SCHEMBL6202588 | 0.79 | CRHR1 (0.38) | CRHR1 | |
| SCHEMBL7474497 | 0.79 | MCHR1 (0.40) | — | |
| SCHEMBL5414915 | 0.79 | CRHR1 (0.47) | CRHR1 | |
| SCHEMBL5409765 | 0.78 | CRHR1 (0.48) | CRHR1 | |
| SCHEMBL7473334 | 0.77 | CRHR1 (0.45) | CRHR1CNR2 | |
| SCHEMBL7477213 | 0.76 | CRHR1 (0.39) | CRHR1 | |
| SCHEMBL6201091 | 0.74 | CRHR1 (0.43) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255740-A2 | SUBSTITUTED ARYLPYRAZINES | NEUROGEN CORPORATION (US) | 2002-11-13 | — | — | EP | claimed |
| WO-2001060806-A2 | SUBSTITUTED ARYLPYRAZINES | NEUROGEN CORPORATION (US) | 2001-08-23 | — | — | WO | claimed |