Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.53 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.53 |
| ▸ | DHODH | Q02127 | 15/20 | 0.52 |
| ▸ | PARP1 | P09874 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7966462 | 0.85 | PKN1 (0.56) | KDM4EPKN1PKN2PARP1 | |
| SCHEMBL8952887 | 0.84 | KDM4E (0.62) | KDM4EHPGDDHODHPARP1 | |
| SCHEMBL28267033 | 0.83 | KDM4E (0.61) | KDM4EHPGDDHODHPARP1 | |
| SCHEMBL7970694 | 0.81 | CHEK1 (0.48) | PKN1PKN2PARP1 | |
| SCHEMBL27720114 | 0.80 | KDM4E (0.57) | KDM4EHPGDPKN1PKN2DHODH | |
| SCHEMBL7422467 | 0.79 | KDM4E (0.54) | KDM4EHPGDPKN1PKN2DHODH | |
| SCHEMBL311504 | 0.79 | KDM4E (0.56) | KDM4EHPGDDHODHPARP1 | |
| SCHEMBL1298127 | 0.76 | PARP1 (0.73) | KDM4EHPGDDHODHPARP1 | |
| SCHEMBL7480899 | 0.76 | PKN1 (0.50) | HPGDPKN1PKN2PARP1 | |
| SCHEMBL9725333 | 0.76 | DHODH (0.77) | KDM4EHPGDDHODHPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946519-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998024771-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-11 | — | — | WO | disclosed |