SCHEMBL311504

SCHEMBL311504

O=C(OC(=O)c1nc2c(C(=O)O)cccc2[nH]1)c1nc2c(C(=O)O)cccc2[nH]1

nearest known ligand 0.56

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.56
HPGD P15428 1/20 0.56
DHODH Q02127 16/20 0.55
PARP1 P09874 3/20 0.54
PARP2 Q9UGN5 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8952887 0.87 KDM4E (0.62) KDM4EHPGDDHODHPARP1
SCHEMBL28267033 0.83 KDM4E (0.61) KDM4EHPGDDHODHPARP1
SCHEMBL27720114 0.83 KDM4E (0.57) KDM4EHPGDDHODHPARP1PARP2
SCHEMBL7422467 0.79 KDM4E (0.54) KDM4EHPGDDHODHPARP1
SCHEMBL7484394 0.79 PKN1 (0.60) KDM4EHPGDDHODHPARP1
SCHEMBL7478700 0.79 KDM4E (0.54) KDM4EHPGDDHODHPARP1
SCHEMBL9725333 0.78 DHODH (0.77) KDM4EHPGDDHODHPARP1
SCHEMBL7863163 0.77 PARP1 (0.63) KDM4EHPGDDHODHPARP1
SCHEMBL28263593 0.77 DHODH (0.53) KDM4EHPGDDHODHPARP1
SCHEMBL8260543 0.76 KDM4E (0.60) KDM4EHPGDDHODHPARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8093349-B2 Terminally modified polybranched polyimide, metal-plated terminally modified polybranched polyimide, and method for producing the same UBE INDUSTRIES, LTD. (JP) 2012-01-10 US disclosed
US-20100009206-A1 TERMINALLY MODIFIED POLYBRANCHED POLYIMIDE, METAL-PLATED TERMINALLY MODIFIED POLYBRANCHED POLYIMIDE, AND METHOD FOR PRODUCING THE SAME UBE INDUSTRIES, LTD. (JP) 2010-01-14 US disclosed