Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.57 |
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470425 | 0.82 | DRD2 (0.44) | DRD2DRD4DRD3NPC1RAB9A | |
| SCHEMBL7485710 | 0.78 | DRD2 (0.76) | DRD2DRD4DRD3 | |
| SCHEMBL9385747 | 0.74 | DRD2 (0.63) | DRD2DRD4DRD3ADRB3 | |
| SCHEMBL7480072 | 0.74 | DRD2 (0.80) | DRD2DRD4DRD3 | |
| SCHEMBL7482710 | 0.73 | DRD2 (0.67) | DRD2DRD4DRD3HTR1A | |
| SCHEMBL7478147 | 0.73 | DRD2 (1.00) | DRD2DRD4DRD3 | |
| SCHEMBL6588799 | 0.71 | DRD2 (0.61) | DRD2DRD4DRD3HTR1A | |
| SCHEMBL9389086 | 0.71 | DRD2 (0.59) | DRD2DRD4DRD3HTR1A | |
| SCHEMBL11225985 | 0.71 | DRD2 (0.52) | DRD2DRD4DRD3HTR1A | |
| SCHEMBL11230293 | 0.71 | DRD2 (0.52) | DRD2DRD4DRD3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923551-B1 | 4-AMINOETHOXY INDOLONE DERIVATIVES | AMERICAN HOME PROD (US) | 2002-06-05 | — | — | EP | claimed |