Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.56 |
| ▸ | RARG | P13631 | 9/20 | 0.56 |
| ▸ | RARA | P10276 | 9/20 | 0.56 |
| ▸ | RXRA | P19793 | 4/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.44 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.43 |
| ▸ | HNF4A | P41235 | 2/20 | 0.43 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701229 | 0.86 | RARB (0.48) | RARBRARGRARARXRA | |
| SCHEMBL6347726 | 0.80 | RARB (0.49) | RARBRARGRARARXRAACMSD | |
| SCHEMBL6348337 | 0.76 | RARB (0.46) | RARBRARGRARARXRAHNF4A | |
| SCHEMBL6348359 | 0.76 | RARB (0.46) | RARBRARGRARARXRAHNF4A | |
| SCHEMBL9551769 | 0.72 | HNF4A (0.55) | RARBRARGRARARXRAHNF4A | |
| SCHEMBL14437917 | 0.72 | RARB (1.00) | RARBRARGRARARXRARXRB | |
| SCHEMBL6338148 | 0.71 | RARB (0.41) | RARBRARGRARARXRAHNF4A | |
| SCHEMBL28646163 | 0.70 | RXRA (0.59) | RARBRARGRARARXRARXRB | |
| SCHEMBL8350702 | 0.70 | RARG (0.64) | RARBRARGRARARXRARXRB | |
| SCHEMBL6340706 | 0.70 | RARB (0.40) | RARBRARGRARARXRAPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977749-B1 | BI-AROMATIC COMPOUNDS AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | GALDERMA RES & DEV (FR) | 2002-03-13 | — | — | EP | disclosed |
| EP-0977749-A1 | BI-AROMATIC COMPOUNDS AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | Galderma Research & Development (FR) | 2000-02-09 | — | — | EP | disclosed |
| WO-1998056783-A1 | BI-AROMATIC COMPOUNDS AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | GALDERMA RESEARCH & DEVELOPMENT (FR) | 1998-12-17 | — | — | WO | disclosed |