Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470805 | 0.93 | TSHR (0.54) | TSHRLMNANPSR1USP2MAPK1 | |
| SCHEMBL7476798 | 0.91 | TSHR (0.51) | TSHRLMNANPSR1USP2MAPK1 | |
| SCHEMBL7470492 | 0.87 | TSHR (0.53) | TSHRLMNANPSR1USP2MAPK1 | |
| SCHEMBL7461596 | 0.85 | TSHR (0.46) | TSHRLMNANPSR1USP2MAPK1 | |
| SCHEMBL7475256 | 0.85 | LMNA (0.45) | TSHRLMNANPSR1USP2MAPK1 | |
| SCHEMBL7472497 | 0.84 | TSHR (0.47) | TSHRLMNANPSR1USP2MAPK1 | |
| SCHEMBL7465749 | 0.82 | GSK3B (0.48) | TSHRLMNANPSR1USP2MAPK1 | |
| SCHEMBL7477248 | 0.82 | KMT2A (0.50) | TSHRLMNANPSR1USP2MAPK1 | |
| SCHEMBL7473395 | 0.80 | KDM4E (0.40) | TSHRLMNANPSR1USP2MAPK1 | |
| SCHEMBL7472359 | 0.79 | CASP1 (0.43) | TSHRLMNANPSR1USP2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-B1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO MCNEIL PHARM INC (US) | 2002-12-18 | — | — | EP | disclosed |
| US-5854242-A | Benzoxazine antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |