SCHEMBL7478940

SCHEMBL7478940

CC(C)C1(C)CS(=O)(=O)c2ccccc2C(c2ccccc2)N1

nearest known ligand 0.55

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC10A2 Q12908 18/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8224360 1.00 SLC10A2 (0.55) SLC10A2
SCHEMBL8193822 1.00 SLC10A2 (0.55) SLC10A2
SCHEMBL8193818 1.00 SLC10A2 (0.55) SLC10A2
SCHEMBL8224359 1.00 SLC10A2 (0.55) SLC10A2
SCHEMBL8692577 0.81 SLC10A2 (0.61) SLC10A2
SCHEMBL8689990 0.81 SLC10A2 (0.61) SLC10A2
SCHEMBL8689994 0.81 SLC10A2 (0.61) SLC10A2
SCHEMBL8378607 0.78 SLC10A2 (0.65) SLC10A2
SCHEMBL12069789 0.78 SLC10A2 (0.65) SLC10A2
SCHEMBL8620064 0.77 SLC10A2 (0.57) SLC10A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0683774-B1 HYPOLIPIDAEMIC COMPOUNDS WELLCOME FOUND (GB) 2002-10-09 EP disclosed
US-5817652-A ATHEROSCLEROSIS GLAXO WELLCOME INC. (US) 1998-10-06 US disclosed
EP-0683773-B1 HYPOLIPIDAEMIC CONDENSED 1,4-THIAZEPINES WELLCOME FOUND (GB) 1997-09-17 EP disclosed
EP-0683773-A1 HYPOLIPIDAEMIC CONDENSED 1,4-THIAZEPINES. WELLCOME FOUND (GB) 1995-11-29 EP disclosed
WO-1994018183-A1 HYPOLIPIDAEMIC CONDENSED 1,4-THIAZEPINES THE WELLCOME FOUNDATION LIMITED (GB) 1994-08-18 WO disclosed