SCHEMBL7478962

SCHEMBL7478962

CC1(C)CC(OCc2ccc(COC3CC(C)(C)N(O)C(C)(C)C3)cc2)CC(C)(C)N1O

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.44
HTT P42858 1/20 0.44
NAAA Q02083 7/20 0.38
CTSL P07711 1/20 0.36
CTSB P07858 1/20 0.36
CTSK P43235 1/20 0.36
OPRM1 P35372 2/20 0.36
OPRL1 P41146 2/20 0.36
CARM1 Q86X55 6/20 0.35
PRMT6 Q96LA8 6/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
KDM4E B2RXH2 1/20 0.34
TMEM97 Q5BJF2 1/20 0.34
SIGMAR1 Q99720 1/20 0.34
PRMT8 Q9NR22 1/20 0.34
HRH3 Q9Y5N1 1/20 0.34
ALDH1A1 P00352 1/20 0.34
ALOX15 P16050 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24850108 0.92 GAA (0.40) GAAHTTNAAACTSLCTSB
SCHEMBL562023 0.92 GAA (0.48) GAAHTTNAAACTSLCTSB
Hydrochloric Acid SCHEMBL4438215 0.90 GAA (0.50) GAAHTTNAAACTSLCTSB
SCHEMBL17075344 0.88 GAA (0.38) GAAHTTNAAACTSLCTSB
SCHEMBL26214909 0.87 CARM1 (0.47) GAAHTTNAAACARM1PRMT6
SCHEMBL24850107 0.86 GAA (0.36) GAAHTTNAAA
SCHEMBL22154463 0.81 GAA (0.33) GAAHTT
SCHEMBL17881233 0.79 ALDH1A1 (0.42) GAAHTTKDM4EALDH1A1ALOX15
SCHEMBL4436046 0.79 KDM4E (0.41) KDM4EALDH1A1
SCHEMBL7476490 0.78 CARM1 (0.36) NAAACTSLCTSBCTSKOPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5006577-A Durable, weatherproof CIBA-GEIGY CORPORATION (US) 1991-04-09 US claimed
EP-0309402-B2 N-substituted hindered amine stabilizers CIBA SC HOLDING AG (CH) 2002-06-12 EP disclosed
EP-0309401-B2 Stabilization of coatings with N-hydroxy hindered amines CIBA SC HOLDING AG (CH) 2002-06-05 EP disclosed
EP-0309402-B1 N-substituted hindered amine stabilizers CIBA GEIGY AG (CH) 1995-01-11 EP disclosed
EP-0309401-B1 Stabilization of coatings with N-hydroxy hindered amines CIBA GEIGY AG (CH) 1994-10-26 EP disclosed
EP-0389422-B1 Stabilizers derived from N-hydroxy hindered amines by Michael addition reactions CIBA GEIGY AG (CH) 1994-09-21 EP disclosed
US-5204473-A O-substituted N-hydroxy hindered amine stabilizers CIBA-GEIGY CORPORATION (US) 1993-04-20 US disclosed
US-5064883-A Stabilization of acid catalyzed thermoset resins with n-hydroxy hindered amines CIBA-GEIGY CORPORATION (US) 1991-11-12 US disclosed
US-5015678-A Light stabilized polymers by the addition of N-hydoxyamines CIBA-GEIGY CORPORATION (US) 1991-05-14 US disclosed
US-5006577-A Durable, weatherproof CIBA-GEIGY CORPORATION (US) 1991-04-09 US disclosed
US-5004770-A Light, heat, and oxygen resistant CIBA-GEIGY CORPORATION (US) 1991-04-02 US disclosed
EP-0389422-A2 Stabilizers derived from N-hydroxy hindered amines by Michael addition reactions CIBA-GEIGY AG (CH) 1990-09-26 EP disclosed
EP-0309402-A1 N-substituted hindered amine stabilizers CIBA-GEIGY AG (CH) 1989-03-29 EP disclosed
EP-0309401-A1 Stabilization of coatings with N-hydroxy hindered amines CIBA-GEIGY AG (CH) 1989-03-29 EP disclosed