SCHEMBL7476490

SCHEMBL7476490

CCON1C(C)(C)CC(OCc2ccc(COC3CC(C)(C)N(OCC)C(C)(C)C3)cc2)CC1(C)C

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 10/20 0.36
PRMT6 Q96LA8 10/20 0.36
NAAA Q02083 4/20 0.35
TMEM97 Q5BJF2 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
PRMT8 Q9NR22 1/20 0.35
HRH3 Q9Y5N1 1/20 0.35
TSHR P16473 2/20 0.34
KMT2A Q03164 1/20 0.34
CTSL P07711 1/20 0.33
CTSB P07858 1/20 0.33
CTSK P43235 1/20 0.33
OPRM1 P35372 1/20 0.33
OPRL1 P41146 1/20 0.33
ALDH1A1 P00352 1/20 0.33
ESR1 P03372 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9240294 0.92 CARM1 (0.44) CARM1PRMT6NAAATMEM97SIGMAR1
SCHEMBL7475314 0.84 CARM1 (0.45) CARM1PRMT6NAAATMEM97SIGMAR1
SCHEMBL9440082 0.83 CARM1 (0.46) CARM1PRMT6NAAATMEM97SIGMAR1
SCHEMBL7478962 0.78 GAA (0.44) CARM1PRMT6NAAATMEM97SIGMAR1
SCHEMBL9335197 0.78 CARM1 (0.42) CARM1PRMT6NAAATMEM97SIGMAR1
SCHEMBL7520600 0.78 KMT2A (0.39) CARM1PRMT6HRH3TSHRKMT2A
SCHEMBL1639896 0.77 CARM1 (0.41) CARM1PRMT6NAAATMEM97SIGMAR1
SCHEMBL8415341 0.75 CARM1 (0.40) CARM1PRMT6TMEM97SIGMAR1PRMT8
SCHEMBL10576735 0.74 NAAA (0.35) CARM1PRMT6NAAATMEM97SIGMAR1
SCHEMBL24246793 0.74 NAAA (0.35) NAAATSHRKMT2ACTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0309400-B1 N-acyloxy hindered amine stabilizers CIBA GEIGY AG (CH) 1994-03-02 EP claimed
US-5124378-A Resin containign N-Hydroxyl hindered amine oxidative and light stabilizers CIBA-GEIGY CORPORATION (US) 1992-06-23 US claimed
US-5096950-A N-alkoxypiperidines CIBA-GEIGY CORPORATION (US) 1992-03-17 US claimed
US-5004770-A Light, heat, and oxygen resistant CIBA-GEIGY CORPORATION (US) 1991-04-02 US claimed
EP-0309400-A2 N-acyloxy hindered amine stabilizers CIBA-GEIGY AG (CH) 1989-03-29 EP claimed
EP-0309402-B2 N-substituted hindered amine stabilizers CIBA SC HOLDING AG (CH) 2002-06-12 EP disclosed
EP-0309402-B1 N-substituted hindered amine stabilizers CIBA GEIGY AG (CH) 1995-01-11 EP disclosed
US-5204473-A O-substituted N-hydroxy hindered amine stabilizers CIBA-GEIGY CORPORATION (US) 1993-04-20 US disclosed
US-5124378-A Resin containign N-Hydroxyl hindered amine oxidative and light stabilizers CIBA-GEIGY CORPORATION (US) 1992-06-23 US disclosed
US-5112890-A Piperidine compound with oxygen bonded to ring nitrogen CIBA-GEIGY CORPORATION (US) 1992-05-12 US disclosed
US-5096950-A N-alkoxypiperidines CIBA-GEIGY CORPORATION (US) 1992-03-17 US disclosed
US-5004770-A Light, heat, and oxygen resistant CIBA-GEIGY CORPORATION (US) 1991-04-02 US disclosed
EP-0309402-A1 N-substituted hindered amine stabilizers CIBA-GEIGY AG (CH) 1989-03-29 EP disclosed