Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL700746 | 0.77 | ALDH1A1 (0.44) | ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL3175492 | 0.73 | HPGD (0.44) | CA1CA2ALDH1A1L3MBTL1 | |
| SCHEMBL8626370 | 0.73 | CRBN (0.41) | ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL11817898 | 0.70 | ALDH1A1 (0.46) | CA12CA1CA2CA6CA5A | |
| SCHEMBL29396692 | 0.68 | ALDH1A1 (0.42) | CA12CA1CA2CA6CA7 | |
| SCHEMBL570014 | 0.67 | CHRNB4 (0.42) | CA1CA2ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL14854458 | 0.67 | MKNK1 (0.41) | — | |
| SCHEMBL28734259 | 0.65 | GAA (0.46) | ALDH1A1TDP1 | |
| SCHEMBL29574369 | 0.65 | GAA (0.46) | ALDH1A1TDP1 | |
| SCHEMBL10343777 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054874-B1 | SUBSTITUTED AMINOPHENYL ISOXAZOLINE DERIVATIVES USEFUL AS ANTIMICROBIALS | UPJOHN CO (US) | 2002-08-28 | — | — | EP | disclosed |
| EP-1054874-A1 | SUBSTITUTED AMINOPHENYL ISOXAZOLINE DERIVATIVES USEFUL AS ANTIMICROBIALS | PHARMACIA & UPJOHN COMPANY (US) | 2000-11-29 | — | — | EP | disclosed |
| US-6069141-A | BACTERICIDES | PHARMACIA & UPJOHN COMPANY (US) | 2000-05-30 | — | — | US | disclosed |
| WO-1999041244-A1 | SUBSTITUTED AMINOPHENYL ISOXAZOLINE DERIVATIVES USEFUL AS ANTIMICROBIALS | PHARMACIA & UPJOHN COMPANY (US) | 1999-08-19 | — | — | WO | disclosed |